New Drugs in MOH Formulary

According to the pekeliling in Dec 2009 by Bahagian Perkhidmatan farmasi, there are some additions to the MOH Formulary.

[Drug name][Category][Indication]

Introduction of New Drug

Inj Cetrorelix 0.25 mg (A*)-Prevention of premature ovulation in pt undergoing a controlled ovarian stimulation, followed by oocyte pick-up and assisted reproductive technique.

Inj Ganirelix 0.25 mg/0.5 mL (A*)- Prevention of premature luteinizing hormone surges in women undergoing controlled ovarian hyperstimulation for assisted reproduction technique.

Inj Carbetoin 100 mcg/mL (A*)- Prevention of uterine atony and postpartum haemorrhage following elective caesarean section uner epidural or spinal anaesthesia.

Cap Dabigatran etexilate 75 mg (A*)- Prevention of venous thromboembolic events in patients who have undergone total knee replacement or total hip replacement surgery.

Cap Dabigatran etexilate 110 mg (A*)- Patients at risk for bleeding, recent bipsy or major trauma, spinal & epidural anaesthesia, lumbar puncture, pregnancy & lactation, children.

Cap Rifampicin 150 mg (B)- Initial phase (2 months) of tuberculosis

Tab Isoniazid 75 mg (B)- Initial phase (2 months) of tuberculosis

Tab Pyrazinamide 400 mg(B)- Initial phase (2 months) of tuberculosis

Tab Paliperidone 3 mg/6 mg/9 mg [extended release] (A)- Second or third line treatment of schizophrenia.

Human Papillomavirus (Types 6, 11, 16, 18) vaccine injection [Gardasil] (A)- For the prevention of cervical cancer due to papilloma virus. To be used as part of the public health programme only.

Human Papillomavirus (Types 16, 18) vaccine injection [Cervarix] (A)- For the prevention of cervical cancer due to papilloma virus. To be used as part of the public health programme only.

Tab Sodium dichloroisocyanurate 2.5 g/5 mg (C)-Low and medium level disinfectant

Addition of Formulation

Typhoid vaccine capsule (B)- Active immunisation against typhoid fever in adult and child 6 years of age or older.

Fentanyl 12 mcg/hr transdermal patch (A*)- As a second line drug in the management of chronic severe cancer pain not responding to non-narcotic analgesic. Not to be use in opioid naïve patients. The use is to be restricted to pain specialists, palliative medicine specialists and oncologists.

Menotrophin 75 IU injection (Follicle Stimulating Hormone 75 IU and Luteinizing Hormone 75 IU) (A*)

Menotrophin, Highly Purified 75 IU injection (Follicle Stimulating Hormone 75 IU and Luteinizing Hormone 75 IU) (A*)-

Treatment of infertility where clomifene has failed or stimulation of follicle growth as part of an assisted reproductive technology.

Addition of Indication

Salmeterol 50 mcg and fluticasone propionate 500 mcg inhalation [Seretide] (A)

Old indication- Regular treatment of reversible obstructive airways disease including asthma

New indication-

· Regular treatment of reversible obstructive airways disease including asthma

· COPD including chronic bronchitis and emphysema

Tab Leflunomide 10 mg/20 mg/100 mg (A*)

Old indication- Persistent active rheumatoid arthritis

New indication-

· Persistent active rheumatoid arthritis

· Active psoriatic arthritis